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Well this thread escalated pretty fast from a 4/20 to Easter.
Maybe I'm misinterpreting, but you make it sound as if the only people doing drugs lead awful/sad lives. The truth is, lots of people lead happy, productive lives and just happen to like to get high for fun. And if they're doing it for the right reasons (ie to have fun, and not to escape some awful/sad life), who cares?
People exercise for fun, is that sad?
People watch reality tv for fun, is that sad?
People post on message boards, is that sad?
Your use of jargon makes me think you're an idiot; If you have to clarify what your comment refers to, you clearly have no clue what you are talking about.
Some people have medical issues, and choose to use marijuana instead of taking drugs that are PROVEN to be more harmful to one's health in the long-term. For example, Tylenol, and other OTC pain relievers, are full of acetaminophen which will easily have a negative impact on your liver/kidneys.
Prescription pills also remain an issue; codeine, oxycodone, hydromorphone, promethazine, alprazolam, benzodiazepine are all commonly abused across North America. These drugs are very physically, and psychologically harmful.
While the political debate of marijuana continues, one fact remains: It poses a risk to pharmaceutical companies, and will not be legalized for this reason. Research is also limited, as the profit potential for legal marijuana is very low.
TL;DR: People's lives are not sad when they use a controlled substance, like marijuana or alcohol, recreationally. They are also not sad if marijuana is a medication. Their lives may even be improved by using marijuana. People with sad lives post comments like yours on the interwebs.